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First Posted Mar 4, 2010
Jan 14, 2012

Evaluation of Diffusion of Triamcinolone Acetonide from the Distal Interphalangeal Joint into the Navicular Bursa in Horses

"Am J Vet Res. 2010 Feb;71(2):169-75.

Evaluation of diffusion of triamcinolone acetonide from the distal interphalangeal joint into the navicular bursa in horses. Boyce M, Malone ED, Anderson LB, Park S, Godden SM, Jenner F, Trumble TN.

Department of Veterinary Population Medicine, College of Veterinary Medicine, University of Minnesota, Saint Paul, MN 55108, USA. boyc0050 @ umn.edu

OBJECTIVE: To determine whether triamcinolone acetonide diffuses from the distal interphalangeal joint (DIPJ) to the navicular bursa, diffusion is direct or systemic, and addition of sodium hyaluronan has an effect on diffusion in horses. ANIMALS: 11 adult horses without forelimb lameness. ...

CONCLUSIONS AND CLINICAL RELEVANCE: Triamcinolone acetonide diffused directly from the DIPJ into the navicular bursa in clinically normal horses, and diffusion was not affected by addition of hyaluronan. Injection into the DIPJ with triamcinolone acetonide or a triamcinolone acetonide-hyaluronan combination can potentially be used for treatment of navicular syndrome, but further studies are needed to determine whether triamcinolone acetonide diffuses similarly in horses with navicular syndrome."

PMID: 20113224 [PubMed - in process] Abstract:PubMed

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